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Heart Health Checkup: Which Blood Tests Can Assess Heart Risk?

Heart Health Checkup: Which Blood Tests Can Assess Heart Risk?

Picture the report landing in your inbox. Read it to yourself, line by line, and discover what a Heart Health Checkup really involves. Firstly, one must understand that a single blood test does not provide a whole picture; major contributors to heart problems include smoking, high blood pressure, high cholesterol and diabetes, so always read your numbers in context. 

Why test your blood for heart risk at all?

Blood holds plenty of clues. High levels of “bad” cholesterol may be a sign of an increased risk of heart attack. Elevated levels of other substances may indicate heart failure, or atherosclerosis, the hardening of arteries. The aim isn’t to scare you. It is all about taking early action, while still in the driver’s seat. Combining your test results with your medical history provides a clearer picture, a foundation for treatment planning.

Before the blood draw: how to prepare

Preparation is easy: find out if you need to fast, as some tests are best taken after a lengthy period without food. For the Lp(a) test, you must not eat anything for 12 hours before, or smoke. Likewise, enquire if and how medications, or supplements may affect the results, and never alter your medicine regime on your own. 

The blood draw takes about a minute, when a phlebotomist inserts a needle into a vein on the inside of your elbow or wrist, and you may feel a brief pinch. Test results take anywhere from a few days to a number of weeks.

The cholesterol panel

Most reports start here. A cholesterol blood test, sometimes called a lipid profile, typically measures total cholesterol, LDL and HDL cholesterol, and triglycerides. LDL, or low-density lipoprotein, is the “bad” cholesterol, which sticks to artery walls, narrowing them, and contributing to heart disease. HDL, or high-density lipoprotein is the “good” cholesterol, which removes the bad cholesterol from the blood, so the higher, the better. Triglycerides are another type of fat in the blood, and high levels of triglycerides also increase the risk of heart disease. 

Many reports also include non HDL cholesterol, which is calculated as total cholesterol minus HDL cholesterol. It may be a better marker of risk than total or LDL cholesterol alone.  Food and drink move triglycerides too. Refined carbohydrates, simple sugars, a high fat diet and alcohol all increase cholesterol, while regular exercise lowers it. 

Inflammation (hsCRP)

Next, hsCRP, or high-sensitivity C-reactive protein, is a protein made by the liver, which rises in response to inflammation. Inflammation makes it easier for plaques to form in blood vessels. Higher than normal levels of CRP are associated with an increased risk of heart attack, stroke, and heart disease.

A cold or a long run can push the number up for a while. That’s why Mayo Clinic says the test should be done twice, two weeks apart.

Lp(a)

Lp(a) is a type of LDL cholesterol. Your genes set the level, and weight, diet and exercise don’t change it. A high level is a recognised risk factor for atherosclerosis, stroke and heart attack. MedlinePlus says US heart association and cardiology college guidelines recommend that every adult get tested once. 

Mayo Clinic adds a note of caution. It isn’t clear how much risk a high level adds, or what lowering it would do. Cleveland Clinic says your doctor may order the test if heart disease runs in your family at an early age. 

Blood sugar

This one surprises people. HbA1c is a form of hemoglobin, an indicator of average blood sugar levels over the past two to three months, and fasting glucose is another test for blood sugar levels. Both detect pre diabetes or diabetes, and both are risk factors for heart disease; a heart health checkup is not complete without them.

The extras

Some checkups add more markers. ApoB may be a better overall risk marker than LDL alone. Elevated levels of homocysteine are also a risk factor, as is fibrinogen, a clotting protein in the blood. Thyroid problems also contribute to heart disease and irregular heartbeats, so a TSH test may be included. Kidney markers matter too, because weak kidneys can stress the heart. If you take cholesterol medicine, liver enzymes and creatine kinase may be checked, since they can run higher on treatment.

Then there are tests that tell a different story. BNP is a protein your heart and blood vessels release under strain, and doctors use it to work out whether breathlessness comes from heart failure. A high sensitivity troponin T test helps diagnose a heart attack, and raised levels have also been linked to higher heart disease risk in people with no symptoms.

Numbers worth knowing

TestA commonly cited aim
Total cholesterolUnder 200 mg/dL
LDLUnder 100 mg/dL, lower if risk is high
HDLOver 40 (men), over 50 (women)
TriglyceridesUnder 150 mg/dL
hsCRPBelow 2.0 mg/L
Lp(a)Below 30 mg/dL, with 50 and above counted as high

Aims vary by person. Your LDL goal depends on your situation. Cleveland Clinic suggests below 70 for people with heart or blood vessel disease, diabetes or very high risk. It suggests below 100 for those with metabolic syndrome or more than one risk factor, and below 130 for low risk. Doctors may also combine your numbers into an ASCVD risk score, which predicts your 10 year risk of atherosclerotic events. 

How to read your results without panicking

One high number isn’t a diagnosis. Cleveland Clinic points out that blood tests aren’t a definitive diagnosis, and if your results show higher risk, your provider may suggest further testing. [2] So look at the whole report, not one line. Check whether any result needs repeating, as with hsCRP. And write your questions down before the appointment, because they’re easy to forget once you’re in the room.

Questions to ask your doctor

Which of my numbers matter most for my age and history?

Do I need any repeat or extra tests, such as Lp(a) or ApoB?

What LDL goal is right for me?

When should I retest?

Who should think about a checkup?

Your doctor may recommend the test if you have a family history of early heart disease, with heart attacks or bypass surgery before age 50. It also applies if you smoke, have diabetes or high blood pressure, are overweight or obese, do not exercise regularly, or eat a poor diet. 

Where a package fits

Packages bundle several of these tests into one visit. LifeCell’s Ayushman Heart Care, for example, is described as a package to monitor cholesterol levels, cardiovascular risk factors and heart health. Before booking any heart health checkup, check the exact tests, price and fasting rules, since they can differ.

Final thoughts

A laboratory report is only a beginning, a conversation starter. Bring it to a doctor, who will interpret the results in conjunction with your age, blood pressure, medical history, and family history. They can advise on changing your habits, as well as what follow-up blood tests to schedule. Usually, small changes to your lifestyle have a bigger impact than any single number on your blood test.